Deputy Head of the National Security and Foreign Policy Commission at the Iranian Parliament Hossein Naghavi Hosseini said on Sunday that the new changes lately introduced to the US administration prove that Washington is planning to overthrow Irans regime. Hosseini said the Iranian diplomatic corps should know that the Americans would not change their position towards Iran, the regime and its revolution. He called on the Iranian Foreign Ministry to take more efficient and radical positions towards Washington, also warning from the consequences of concessions, in a sign to European-American efforts to adopt sanctions against Iran over its ballistic missile program and its destabilizing role in the region. Last week, US President Donald Trump said that former UN Ambassador John Bolton would take over from H.R. McMaster as national security adviser beginning on April 9. His decision came after the appointment of former CIA chief Mike Pompeo as the new US secretary of state, replacing Rex Tillerson. Hosseini told the semiofficial ISNA news agency that Boltons appointment "proves that the ultimate US objective is to overthrow the Iranian government." For his part, the secretary of the countrys Supreme National Security Council, Ali Shamkhani, was quoted by the semiofficial Fars news agency as saying that attempts by the US to weaken Iran have only "laid the groundwork for improving the power and influence" of Iran. Meanwhile, Iranian President Hassan Rouhani defended his governments policy in implementing the Nuclear Deal. “Over the past 14 months, the Americans have made extensive attempts to undercut and terminate the JCPOA but to no avail,” Rouhani said Sunday on the first work day of the new Iranian year. He added that this was a major success for Iran’s government and foreign policy. The nuclear agreement between Iran and the Group 5+1 was reached in July 2015 and came into force in January 2016.