European powers were dismayed on Tuesday with President Donald Trump’s decision to withdraw from the Iran nuclear deal. His announcement on Tuesday dealt a blow to intense diplomatic efforts that were aimed at dissuading him from going through with the pullout. "France, Germany, and the UK regret the US decision to leave the JCPOA (Iran deal). The nuclear non-proliferation regime is at stake," Frances President Emmanuel Macron wrote. Diplomats had seen the deal as the best way of keeping tabs on Irans ambitions while heading off the risk of a destabilizing new arms race in the Middle East. "We will work collectively on a broader framework, covering nuclear activity, the post-2025 period, ballistic activity, and stability in the Middle East, notably Syria, Yemen, and Iraq," Macron added. The governments of France, Germany and Britain “remain committed to ensuring the agreement is upheld, and will work with all the remaining parties to the deal to ensure this remains the case including through ensuring the continuing economic benefits to the Iranian people that are linked to the agreement," they said in a joint statement. "We encourage Iran to show restraint in response to the decision by the US; Iran must continue to meet its own obligations under the deal," it added. The European Unions chief diplomat Federica Mogherini, who helped oversee the talks with Iran that led to the Joint Comprehensive Plan of Action, insisted the accord "is delivering on its goal which is guaranteeing that Iran doesnt develop nuclear weapons." And she added: "the European Union is determined to preserve it." She made a direct appeal to the Iranian people and their leaders to stick with the accord after Trump said Washington was ditching the "defective" agreement. "Stay true to your commitments as we will stay true to ours and together with the rest of the international community we will preserve this nuclear deal," Mogherini said at a hastily-arranged press conference in Rome. UN Secretary-General Antonio Guterres urged the other signatories of the Iran nuclear deal to stick to their commitments after the US exit from the accord. "I call on other JCPOA participants to abide fully by their respective commitments under the JCPOA and on all other member-states to support this agreement," Guterres said in a statement. Irans President Hassan Rouhani was furious, accusing Trump of "psychological warfare" and vowing to take the matter up with the agreements other signatories, including Washingtons rivals Moscow and Beijing. He said Iran could resume uranium enrichment "without limit" in response to Trumps decision. "I have instructed the Iranian Atomic Energy Organization to take the necessary measures for future actions so that if necessary we can resume industrial enrichment without limit," he said on state television. "We will wait several weeks before applying this decision. We will speak with our friends and allies, the other members of the nuclear agreement," he said. A spokesman for Turkish President Recep Tayyip Erdogan said on Tuesday that the US decision to unilaterally withdraw from the deal will cause instability and new conflicts. In a tweet, Ibrahim Kalin also said the multilateral agreement would continue with the other nations and added that Turkey would continue to oppose all forms of nuclear weapons.