The European Union said Wednesday it "will spare no efforts" in its attempts to keep alive an international deal preventing Iran from developing atomic weapons. EU Commission President Ursula von der Leyen said her foreign affairs chief Josep Borrell will continue to work "in the midterm" to reach out to all participants in the global deal in the hopes that the 2015 nuclear agreement can still be saved despite a rollback on commitments from Tehran. Von der Leyen also reiterated the need to de-escalate the tension in the region, especially after Irans missile attack on two American bases in response to a US strike that killed its top general. She called for an immediate end to the use of weapons in the Middle East conflict between Iran and the United States, urging efforts to restart dialogue. "The use of weapons must stop now to give space for dialogue," she told reporters after a meeting of her commissioners. "We are called upon to do everything possible to rekindle talks. There cannot be enough of that. We have established and time-tested relations with many actors in the region and beyond to de-escalate the situation," she said Speaking alongside von der Leyen, Borrell urged all parties involved in the growing tensions to eschew more military action. "The latest rocket attack on airbases in Iraq used by US and coalition forces, among them European, is yet another example of escalation and increased confrontation. It is in no one´s interest to turn up the spiral of violence even further," he said. Borrell has invited Iran Foreign Minister Javad Zarif to Brussels for talks. The EU foreign ministers have organized a special meeting on Friday to discuss the ongoing crisis. After its top general was assassinated in the US drone attack, Iran announced over the weekend that it would no longer respect limits set on how many centrifuges it can use to enrich uranium. Zarif said the move was a "remedial step" taken within the framework of the nuclear deal and he said it could be reversed.