Maryo Mogannam snuck into the Empire theater in San Francisco with his older cousins to watch "Animal House" when he was 14. He watched most of the James Bond movies at the historic art house and took his wife there on some of their first dates. The cinema, which had been showing movies since the silent film era, served notice in February that it was permanently closing because of the impact of COVID-19. The marquee is now blank, and cardboard and paper cover the box office window. "It"s kind of like losing a friend," said Mogannam, now 57, who owns a retail shipping outlet near the theater, which had been renamed the CineArts at the Empire. As vaccinated Americans emerge from their homes, they also may find their neighborhood theater is not there to greet them. An eight-cinema chain in New England said it will not reopen. The same fate hit a Houston art house beloved by director Richard Linklater and, in a shock to Hollywood, more than 300 screens run by Los Angeles-based Pacific Theatres. That includes the Cinerama Dome, a landmark that hosted several red-carpet movie premieres. Following a year of closures, theaters face deferred rent bills plus media companies" focus on drawing customers to streaming services. Up to one-fourth of the roughly 40,000 screens in the United States could disappear in the next few years, Wedbush Securities analyst Michael Pachter said. The National Association of Theatre Owners rejects that estimate, spokesman Patrick Corcoran said, noting that similar dire warnings accompanying the advent of television and the switch to digital screens never came to pass. Hollywood filmmakers want cinemas to thrive. "It"s the only place where the art dominates," said "Avatar" director James Cameron. "When you watch something on streaming, the other people in the room with you are welcome to interject, to pause to go to the bathroom, to text." At theaters, "we literally make a pact with ourselves to go and spend two to three hours in a focused enjoyment of the art." "For 300 people to laugh and cry at the same time, strangers, not just your family in your house, that"s a very powerful thing," said Chloe Zhao, Oscar-nominated director of best picture nominee "Nomadland." At the Academy Awards on Sunday, the movie industry will "make a case for why cinema matters," producer Stacey Sher said. While acknowledging the hardship of the pandemic, "we also have to fight for cinema and our love of it and the way it has gotten us through things," she said. Director James Cameron poses for a portrait in Manhattan Beach, California April 8, 2014. REUTERS/Lucy Nicholson A woman walks along an empty sidewalk by the closed Eagle movie theater as the spread of the coronavirus disease (COVID-19) continues, in Chadron, Nebraska, U.S., April 15, 2020. REUTERS/Shannon Stapleton/File Photo A pedestrian walks past a closed CineArts Empire theater in San Francisco, California, U.S. April 14, 2021. Picture taken April 14, 2021. REUTERS/Nathan Frandino 1/5 A woman walks along an empty sidewalk by the closed Eagle movie theater as the spread of the coronavirus disease (COVID-19) continues, in Chadron, Nebraska, U.S., April 15, 2020. REUTERS/Shannon Stapleton/File Photo About 58% of theaters have reopened in the United States and Canada, most restricted to 50% capacity or less. The biggest operators - AMC (AMC.N), Cinemark (CNK.N) and Cineworld (CINE.L) - make up roughly half the overall market. Industry leaders project optimism, forecasting a big rebound after restrictions ease and studios unleash new blockbusters. Coming attractions include a new Bond adventure, the ninth "Fast & Furious" film, a "Top Gun" sequel and several Marvel superhero movies. "Avatar 2," Cameron"s follow-up to the highest-grossing film of all time, is set to debut in December 2022. Some box office analysts predict 2022 ticket sales will hit a record. Supporters point to late March release "Godzilla vs. Kong," which brought in roughly $48.5 million at U.S. and Canadian box offices over its first five days, even though audiences could stream it on HBO Max. "That was a big win for the entire industry," said Rich Daughtridge, president and chief executive of Warehouse Cinemas in Frederick, Maryland. But near- and long-term challenges loom, particularly for smaller cinemas. Theaters are negotiating with landlords over back rent. A federal aid program was delayed due to technical problems. Plus, media companies are bringing movies to homes sooner. Executives say streaming is their priority, pouring billions into programming made to watch in living rooms as they compete with Netflix Inc (NFLX.O). Most at risk are theaters with one or two screens, Wedbush Securities" Pachter said. He said his best guess is between 5,000 and 10,000 screens could go permanently dark in coming years. "I think we"ll see a gradual decline in the number of screens," Pachter said, "just like we"ve seen a gradual decline in the number of mom-and-pop grocery stores and bookstores."