Two cases of human-to-cat transmission of Covid-19 have been identified by researchers. Scientists from the University of Glasgow found the cases of Sars-CoV-2 transmission as part of a screening programme of the feline population in the UK. The cats, of different breeds, were living in separate households and displayed mild to severe respiratory signs. Researchers believe both pets were infected by their owners, who had Covid-19 symptoms before the cats became unwell. The study, published in the Veterinary Record, says there is no evidence of cat-to-human transmission or that cats, dogs or other domestic animals play any appreciable role in the epidemiology of human Covid infections. But the scientists said domestic animals could act as a “viral reservoir”, allowing continued transmission, and said it was important to improve understanding of whether pets can play a role in infecting humans. Prof Margaret Hosie, from the MRC-University of Glasgow’s centre for virus research and lead author of the study, said: “These two cases of human-to-animal transmission, found in the feline population in the UK, demonstrate why it is important that we improve our understanding of animal Sars-CoV-2 infection. “Currently, animal-to-human transmission represents a relatively low risk to public health in areas where human-to-human transmission remains high. However, as human cases decrease, the prospect of transmission among animals becomes increasingly important as a potential source of Sars-CoV-2 reintroduction to humans. “It is therefore important to improve our understanding of whether exposed animals could play any role in transmission.” Researchers at the centre worked in partnership with the Veterinary Diagnostic Service (VDS) at the university’s School of Veterinary Medicine on the study. The first cat was a four-month-old female Ragdoll kitten from a household in which the owner developed symptoms that were consistent with Sars-CoV-2 infection at the end of March 2020, although they were not tested. The kitten was taken to a vet with breathing difficulties in April 2020 but its condition deteriorated and it had to be put down. Postmortem lung samples revealed damage consistent with a viral pneumonia and there was evidence of Sars-CoV-2 infection. The second cat was a six-year-old female Siamese from a household where one owner tested positive for Covid-19. The cat was taken to the vet with nasal discharge and conjunctivitis, but its symptoms remained mild and the cat later recovered. Covid-19 infection was confirmed in a retrospective survey of swabs submitted to VDS between March and July 2020 for routine pathogen testing. Scientists believe the two cases are likely to underestimate the true frequency of human-to-animal transmission, as animal testing is limited.