Palestinians fired uninterrupted barrages of rockets into Israel, as its military pounded Gaza with air strikes through the early hours of Tuesday, in a dramatic escalation of clashes in Jerusalem. Explosions shook buildings throughout Gaza and rocket sirens sent Israelis in many southern towns scurrying for shelter overnight. Two Palestinians were killed and more than 100 wounded in air strikes, Palestinian officials said. loading Six Israelis were wounded by a rocket, medics said. Nine children were among the 20 dead in Gaza on Monday and scores of rockets were launched into Israel, many that were intercepted by missile defences. The events were unleashed by Gaza militants firing on the Jerusalem area for the first time since a 2014 war, crossing what Israeli Prime Minister Benjamin Netanyahu called a "red line". The upsurge in violence came as Israel celebrated “Jerusalem Day”, marking its capture of East Jerusalem in the 1967 Arab-Israeli war. The escalation began with confrontations at Al-Aqsa Mosque in the heart of the walled Old City on the compound known to Jews as Temple Mount and to Muslims as the Noble Sanctuary - the most sensitive site in the Israel-Palestinian conflict. loading The Palestine Red Crescent Society said more than 300 Palestinians were injured in clashes with Israeli police, who fired rubber bullets, stun grenades and tear gas in the compound. Police said 21 officers were hurt in the skirmishes. Although the trouble died down after a few hours, there were other focal points of tension, such as the Sheikh Jarrah neighbourhood of East Jerusalem just north of the Old City, where several Palestinian families face eviction from homes claimed by Jewish settlers in a long-running legal case. A picture taken with a drone shows the site of an Israeli air strike amid a flare-up of Israeli-Palestinian violence, in Gaza City May 11, 2021. REUTERS/Mohammed Salem Flames and smoke rise during Israeli air strikes amid a flare-up of Israel-Palestinian violence, in the southern Gaza Strip May 11, 2021. REUTERS/Ibraheem Abu Mustafa People are reflected in a puddle of water mixed with blood at the scene where Palestinians were killed amid a flare-up of Israeli-Palestinian violence, in the northern Gaza Strip May 10, 2021. REUTERS/Mohammed Salem TPX IMAGES OF THE DAY 1/9 Flames and smoke rise during Israeli air strikes amid a flare-up of Israel-Palestinian violence, in the southern Gaza Strip May 11, 2021. REUTERS/Ibraheem Abu Mustafa Hamas, the Islamist militant group that controls Gaza, set an evening deadline for Israel to remove its police from Al-Aqsa and Sheikh Jarrah. When it expired, sirens wailed in Jerusalem and rockets pounded the city"s outskirts. loading Israel views all of Jerusalem as its capital, including the eastern part annexed after the 1967 war in a move that has not secured international recognition. Palestinians want East Jerusalem for the capital of a state they seek in Gaza and the Israeli-occupied West Bank. Hamas and the smaller Islamic Jihad militant group claimed responsibility for the rocket fire on Jerusalem. The Israeli military said it struck targets that included militant operatives, attack tunnels and the home of a Hamas battalion commander. Of the 20 Palestinians killed on Monday, seven, including three children, were family members who died in an explosion in the town of Beit Hanoun, though it was unclear if it had been cause by an Israeli strike or a Palestinian rocket that had fallen short. loading An Israeli military spokesman said about a third of the Palestinian rockets fired had fallen short and caused damage and casualties inside Gaza. International efforts to stem the violence appeared to have already. A Palestinian official told Reuters that Egypt, Qatar and the United Nations, which have mediated truces between Israel and Hamas in the past, were in contact with the group"s leader Ismail Haniyeh. Tension had been building for weeks during the Muslim holy month of Ramadan, amid clashes between Israeli security forces and Palestinian protesters prompting international concern that events could spiral out of control.