Over 96% of people build antibodies after single COVID-19 jab: Study

  • 5/18/2021
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Lead author: ‘It’s a real feat of science in the face of the most devastating pandemic in a century’ ‘How well these vaccines work is remarkable, especially given the speed at which they’ve been developed’ LONDON: More than 96 percent of people develop coronavirus antibodies after receiving only a single dose of the AstraZeneca or Pfizer vaccine, new research has revealed. The England- and Wales-based study, which monitored more than 8,000 participants, also discovered that almost 100 percent of people develop immune cells to successfully fight off coronavirus after two vaccine doses. Researchers found that 96.42 percent of people who received the AstraZeneca or Pfizer vaccine developed antibodies 28-34 days after a first dose. The figure grew to 99.08 percent within seven to 14 days of receiving a second jab, The Guardian newspaper reported. “This is one of the earliest real-world vaccine studies in the UK and it is fantastic news,” said Dr. Maddie Shrotri, lead author of the research paper. “More than nine out of 10 adults in the UK who had either the Pfizer or AstraZeneca vaccine produced antibodies against the virus within a month of their first shot,” she added. “How well these vaccines work is remarkable, especially given the speed at which they’ve been developed. It’s a real feat of science in the face of the most devastating pandemic in a century.” The study, conducted by University College London (UCL) scientists, could have positive implications on the worldwide fight against the coronavirus pandemic. It will be placed through a peer review process before submission to a medical journal. UCL scientists found that both vaccines were equally capable of triggering the antibody response that can ward off severe coronavirus infections. However, antibody levels after a single jab were discovered to be lower in older people and those with underlying health conditions, including cancer, diabetes and heart disease. That discrepancy was later resolved after participants received a second vaccine dose. The study is a “timely reminder” about the importance of receiving a second dose, said Prof. Rob Aldridge, chief investigator of the UCL study. “But it is also reassuring — vaccines are our way out of the pandemic.”

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