LONDON, Oct 6 (Reuters) - Netflix (NFLX.O) Western "The Harder They Fall" opened the London Film Festival on Wednesday, with an all-star red carpet kicking off the return to glitzy in-person premieres at the annual event following a mainly virtual 2020 version. Oscar winner Regina King, "Luther" star Idris Elba and "Da 5 Bloods" actor Jonathan Majors feature in the movie about an outlaw who joins forces with his old gang to hunt down a crime boss recently freed from jail. The movie, whose cast also includes "Joker" actress Zazie Beetz and Oscar nominee LaKeith Stanfield, is inspired by real-life African American cowboys. "It feels amazing ... "The Harder They Fall" lived in my head for so long ever since I was a child," director Jeymes Samuel told Reuters. "The characters in it are all real characters. The story is fictional. I assembled them all in one place, one time, like the Avengers." Elba, who was joined on the red carpet by his co-stars as well as rapper Jay-Z, a producer on the film, plays crime boss Rufus Buck, a role he described as "completely different" to his to his role as a murder detective in popular television series "Luther". "I was like to try and give a spectrum to the fans, so people see me in different roles," he said. "This is a bad guy ... and it’s in a Western and I love Westerns." The 65th edition of the festival will feature 159 feature films, including 21 world premieres over 12 days. Stars of hugely popular television drama "Succession" will also premiere its third series. Highly anticipated films showing at the festival include "Spencer", starring Kristen Stewart as the late Princess Diana, Wes Anderson"s love letter to journalism "The French Dispatch" and coming-of-age drama "The Tender Bar" directed by George Clooney. "The Tragedy of Macbeth", starring Oscar winners Denzel Washington and Frances McDormand, will close the festival on Oct. 17. Reporting by Sarah Mills; Additional reporting by Marie-Louise Gumuchian; Writing by Marie-Louise Gumuchian; Editing by Lisa Shumaker