A Japanese health ministry panel on Friday recommended approval of the COVID-19 antiviral pill developed by Merck & Co Inc, part of Prime Minister Fumio Kishidas plan to roll out new treatments by year-end as concerns rise about the Omicron variant. The panels decision sets the stage for shipments of 200,000 doses across the country from this weekend, based on preparations announced earlier by Kishida. "Im convinced the distribution of this drug is a major step forward for our nations COVID-19 handling," health minister Shigeyuki Goto told reporters after the decision, adding that some medical institutions and pharmacies will start receiving the pill as soon as next Monday. Japan is betting heavily on oral treatments to keep serious infections and deaths at bay should a feared sixth wave of the pandemic emerge. The government agreed last month to pay Merck and its partner Ridgeback Biotherapeutics about $1.2 billion for 1.6 million courses of their drug molnupiravir. In addition, Kishida announced last week a deal to procure 2 million doses of a separate antiviral pill developed by Pfizer Inc. And Japans Shionogi & Co is expected to soon file for approval of its own treatment, supplying another 1 million doses by early next year. US regulators on Thursday authorized the Merck pill for certain high-risk adult patients. Countries rushed to buy Mercks molnupiravir after very promising initial results, but subsequent company data in late November indicated the drug was markedly less effective than previously thought. France cancelled its order on Wednesday. Asked about the debate over its efficacy, Goto said on Friday the Japanese panel evaluated the use of molnupiravir based mainly on the earlier test result, while adding the updated result "does not negate this drugs effectiveness". Japan this week confirmed the first known cases of Omicron infections that could not be traced back to overseas travelers. Community transmissions of the variant have now been found in the western cities of Osaka and Kyoto, and a suspected case was announced in Tokyo on Friday.