Patient safety in healthcare has been and is still a serious global concern. Although patient safety has been on the forefront of public health policy makers’ priorities since the turn of the century, still more international focus, research and debate is needed to improve patient safety. There have been very limited opportunities for international experts to engage with Ministers of Health and other high-ranking political decision-makers, or for effective collaboration between countries. The apparent risk in healthcare has led many countries to invest in several measures to strengthen their healthcare systems and improve patient safety. Efforts were initiated in 2015, which culminated in the launch of the Global Ministerial Patient Safety Summit series, with the first summit being held in London in 2016, followed by Bonn in 2017 and Tokyo in 2018, where international experts engaged with policymakers to promote and sustain a collaborative approach to improve patient safety, globally. The Jeddah Declaration on Patient Safety is founded on the principles that guided the 4th Global Ministerial Patient Safety Summit 2019, Jeddah, Kingdom of Saudi Arabia, which in turn, sets recommendations for international standards, guidelines and actions that aim to address patient safety issues of global significance, with a strong emphasis on Low- and Middle-Income Countries (LMIC). The Summit is thus establishing patient safety as a crucial principle integrated on the efforts to achieve universal health coverage (UHC). The Jeddah Declaration on Patient Safety is a call for action on many fronts, and for many actors, at all levels of healthcare provision and delivery – from frontline, to organizational and policy arenas. The Declaration is founded on the underlying spirit that it is imperative to reflect on the effectiveness of current practices in light of the now mature patient safety evidence base of 20 years; and to collectively move forward with a vision to sustainable and scalable implementation of patient safety solutions known to improve care delivery systems, patient outcomes, and safety culture. The Declaration signals a strong collective and global commitment to shape truly safer systems for generations to come. --SPA 19:42 LOCAL TIME 16:42 GMT 0019 www.spa.gov.sa/w847130